Search results for "CHRONIC PANCREATITIS"

Total pancreatectomy: indications, operative technique, and results: a single centre experience and review of literature.

2010

The aims of this study were to identify the indications to perform a total pancreatectomy and to evaluate the outcome and quality of life of the patient who underwent this operation. A retrospective analysis of a prospective database, regarding all the patients who underwent total pancreatectomy from January 2006 to June 2009, was carried out. Perioperative and outcome data were analyzed in two different groups: ductal adenocarcinoma (group 1) and non-ductal adenocarcinoma (group 2). Twenty (16.9%) total pancreatectomies out of 118 pancreatic resections were performed. Seven (35.0%) patients were affected by ductal adenocarcinoma (group 1) and the remaining 13 (65.0%) by pancreatic diseases…

Hroniska pankreatīta ķirurģiskās ārstēšanas rezultāti: sešu gadu pieredze Rīgas Austrumu klīniskās universitātes slimnīcas, stacionārā "Gaiļezers"

2022

Ievads. Hronisks pankreatīts (HP) ir progresējoša iekaisuma slimība aizkuņģa dziedzerī, kas rada neatgriezenisku dziedzera audu atrofiju un fibrozi. Tas pakāpeniski rada eksokrīnu un endokrīnu aizkuņģa dziedzera mazspēju. Slimībai progresējot, pastiprinoties sāpju sindromam, aizkuņģa dziedzerī attīstās arī lokālas komplikācijas. Iepriekšminētais rada indikācijas ķirurģiskai ārstēšanai. Iespējamo operāciju veidi iedalās divās grupās: rezecējošas un drenējošas. Kopumā aizkuņģa dziedzera operācijas ir tehniski izaicinošas un augsti invazīvas, līdz ar to asociējas ar nozīmīgu pēcoperācijas komplikāciju risku (53,3 %). Darba mērķis. Retrospektīvi noskaidrot ķirurģiskās ārstēšanas veidus un intra…

StellaTUM: current consensus and discussion on pancreatic stellate cell research

2011

The field of pancreatic stellate cell (PSC) biology is very young, as the essential in-vitro tools to study these cells (ie, methods to isolate and culture PSC) were only developed as recently as in 1998. Nonetheless, there has been an exponential increase in research output in this field over the past decade, with numerous research groups around the world focusing their energies into elucidating the biology and function of these cells. It is now well established that PSC are responsible for producing the stromal reaction (fibrosis) of two major diseases of the pancreas—chronic pancreatitis and pancreatic cancer. Despite exponentially increasing data, the methods for studying PSC remain var…

Inflammatory and tumor-like lesions of the pancreas

2020

Summary Inflammatory/tumor-like lesions of the pancreas represent a heterogeneous group of diseases that can variably involve the pancreatic gland determining different signs and symptoms. In the category of inflammatory/tumor-like lesions of the pancreas, the most important entities are represented by chronic pancreatitis, which includes alcoholic, obstructive and hereditary pancreatitis, paraduodenal (groove) pancreatitis, autoimmune pancreatitis, lymphoepithelial cyst, pancreatic hamartoma and intrapancreatic accessory spleen. An in-depth knowledge of such diseases is essential, since they can cause severe morbidity and may represent a potential life-threatening risk for patients. Furthe…

Italian consensus guidelines for chronic pancreatitis

2010

Aknu steatozes saistība ar hroniska pankreatīta gaitu

2019

Ievads. Hronisks pankreatīts ir hroniska iekaisīga aizkuņģa dziedzera slimība, kas var novest līdz eksokrīnai un endokrīnai mazspējai. Literatūrā ir atrodami maz dati par aknu steatozes prevalenci hroniska pankreatīta pacientu vidū, lai gan abām šīm slimībām ir kopīgi etioloģiskie faktori. Darba mērķis. Analizēt aknu steatozes prevalenci HP slimniekiem un novērtēt aknu steatozes asociāciju ar HP smaguma pakāpi un komplikācijām. Metodes un materiāli. Pētījums bija retrospektīvs šķērsgriezuma pētījums. Tajā tika iekļauti pacienti no PSKUS Gastroenteroloģijas, hepatoloģijas un uztura terapijas centra, laika periodā no 2016. gada līdz 2019. gadam. Tika apkopoti tādi klīniskie parametri kā demog…

Smoking as a cofactor for causation of chronic pancreatitis: a meta-analysis.

2010

Objectives To assess the evidence for tobacco smoking as a risk factor for the causation of chronic pancreatitis. Methods We performed a meta-analysis with random-effects models to estimate pooled relative risks (RRs) of chronic pancreatitis for current, former, and ever smokers, in comparison to never smokers. We also performed dose-response, heterogeneity, publication bias, and sensitivity analyses. Results Ten case-control studies and 2 cohort studies that evaluated, overall, 1705 patients with chronic pancreatitis satisfied the inclusion criteria. When contrasted to never smokers, the pooled risk estimates for current smokers was 2.8 (95% confidence interval [CI], 1.8-4.2) overall and 2…